This page in Swedish

Thomas Chaillou

Position: Senior Lecturer School/office: School of Health Sciences

Email: dGhvbWFzLmNoYWlsbG91O29ydS5zZQ==

Phone: +46 19 303460

Room: G2108

Research subject

Sport Science

About Thomas Chaillou

Thomas Chaillou is a senior lecturer in exercise physiology.

In 2011, he obtained a PhD (University of Grenoble, France) on muscle remodeling during hypertrophy and regeneration in hypoxia. Between 2012 and 2014, he was a post-doctoral fellow at the University of Kentucky (USA) where he continued to develop his expertise on the mechanisms controlling skeletal muscle mass. Between 2014 and 2016, he performed a second postdoc at Karolinska Institute during which he focused his research on muscle function (force, fatigue, recovery) under physiological (e.g., exercise) and pathological (e.g., cancer, chemotherapy, ALS and ischemia) conditions. He became a senior lecturer at Örebro University in 2016.

His current research focuses on three main topics: 1) muscle and molecular biology under physiological (e.g., exercise, aging, thermal stress) and pathological (e.g., inflammation) conditions, 2) recovery strategies in sport and 3) physiological responses and adaptations to exercise.

His teaching primarily focuses on exercise physiology, sport performance, sport nutrition, research methods in Sports Science, and physiological/biological methods applied to Sports Science. He is involved and supervise students in different programs (Bachelor and Master levels) where he is responsible for several courses.

Active projects

Completed projects

Research groups

Exercise Physiology and Sport Medicine (EPSM)

Publications

Articles in journals | Articles, reviews/surveys | Conference papers |

Articles in journals

Treigyte, V. , Chaillou, T. , Eimantas, N. , Venckunas, T. & Brazaitis, M. (2024). Passive heating-induced changes in muscle contractile function are not further augmented by prolonged exposure in young males experiencing moderate thermal stress. Frontiers in Physiology, 15. [BibTeX]
Treigyte, V. , Eimantas, N. , Venckunas, T. , Brazaitis, M. & Chaillou, T. (2023). Moderate muscle cooling induced by single and intermittent/prolonged cold-water immersions differently affects muscle contractile function in young males. Frontiers in Physiology, 14. [BibTeX]
Gineste, C. , Youhanna, S. , Vorrink, S. U. , Henriksson, S. , Hernández, A. , Cheng, A. J. , Chaillou, T. , Buttgereit, A. & et al. (2022). Enzymatically dissociated muscle fibers display rapid dedifferentiation and impaired mitochondrial calcium control. iScience, 25 (12). [BibTeX]
Mader, T. , Chaillou, T. , Alves, E. S. , Jude, B. , Cheng, A. J. , Kenne, E. , Mijwel, S. , Kurzejamska, E. & et al. (2022). Exercise reduces intramuscular stress and counteracts muscle weakness in mice with breast cancer. Journal of Cachexia, Sarcopenia and Muscle, 13 (2), 1151-1163. [BibTeX]
Chaillou, T. , Treigyte, V. , Mosely, S. , Brazaitis, M. , Venckunas, T. & Cheng, A. J. (2022). Functional Impact of Post-exercise Cooling and Heating on Recovery and Training Adaptations: Application to Resistance, Endurance, and Sprint Exercise. Sports medicine - open, 8 (1). [BibTeX]
Järvinen, L. , Lundin Petersdotter, S. & Chaillou, T. (2022). High-intensity resistance exercise is not as effective as traditional high-intensity interval exercise for increasing the cardiorespiratory response and energy expenditure in recreationally active subjects. European Journal of Applied Physiology, 122 (2), 459-474. [BibTeX]
Kamandulis, S. , Mickevicius, M. , Snieckus, A. , Streckis, V. , Montiel Rojas, D. , Chaillou, T. , Westerblad, H. & Venckunas, T. (2022). Increasing the resting time between drop jumps lessens delayed-onset muscle soreness and limits the extent of prolonged low-frequency force depression in human knee extensor muscles. European Journal of Applied Physiology, 122 (1), 255-266. [BibTeX]
Ramos, C. , Cheng, A. J. , Kamandulis, S. , Subocius, A. , Brazaitis, M. , Venckunas, T. & Chaillou, T. (2021). Carbohydrate restriction following strenuous glycogen-depleting exercise does not potentiate the acute molecular response associated with mitochondrial biogenesis in human skeletal muscle. European Journal of Applied Physiology, 121 (4), 1219-1232. [BibTeX]
Liu, Z. , Chaillou, T. , Santos Alves, E. , Mader, T. , Jude, B. , Ferreira, D. M. S. , Hynynen, H. , Cheng, A. J. & et al. (2021). Mitochondrial NDUFA4L2 is a novel regulator of skeletal muscle mass and force. The FASEB Journal, 35 (12). [BibTeX]
Cheng, A. J. , Chaillou, T. , Kamandulis, S. , Subocius, A. , Westerblad, H. , Brazaitis, M. & Venckunas, T. (2020). Carbohydrates do not accelerate force recovery after glycogen-depleting followed by high-intensity exercise in humans. Scandinavian Journal of Medicine and Science in Sports, 30 (6), 998-1007. [BibTeX]
Chaillou, T. & Treigyte, V. (2020). Cold water immersion puts the chill on muscle protein synthesis after resistance exercise. Journal of Physiology, 598 (6), 1123-1124. [BibTeX]
Chaillou, T. , Sanna, I. & Kadi, F. (2020). Glutamine-stimulated in vitro hypertrophy is preserved in muscle cells from older women. Mechanisms of Ageing and Development, 187. [BibTeX]
Cheng, A. J. , Allodi, I. , Chaillou, T. , Schlittler, M. , Ivarsson, N. , Lanner, J. T. , Thams, S. , Hedlund, E. & et al. (2019). Intact single muscle fibres from SOD1(G93A) amyotrophic lateral sclerosis mice display preserved specific force, fatigue resistance and training-like adaptations. Journal of Physiology, 597 (12), 3133-3146. [BibTeX]
Vechetti, I. J. , Wen, Y. , Chaillou, T. , Murach, K. A. , Alimov, A. P. , Figueiredo, V. C. , Dal-Pai-Silva, M. & McCarthy, J. J. (2019). Life-long reduction in myomiR expression does not adversely affect skeletal muscle morphology. Scientific Reports, 9 (1). [BibTeX]
Ferreira, D. M. S. , Cheng, A. J. , Agudelo, L. Z. , Cervenka, I. , Chaillou, T. , Correia, J. C. , Porsmyr-Palmertz, M. , Izadi, M. & et al. (2019). LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force. Skeletal Muscle, 9 (1). [BibTeX]
Chaillou, T. & Cheng, A. J. (2019). Mechanisms of prolonged low-frequency force depression: in-vivo studies get us closer to the truth. American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 316 (5), R502-R503. [BibTeX]
Rantala, R. & Chaillou, T. (2019). Mild hypothermia affects the morphology and impairs glutamine-induced anabolic response in human primary myotubes. American Journal of Physiology - Cell Physiology, 317 (1), C101-C110. [BibTeX]
Chaillou, T. & Cheng, A. (2017). A dose of 5,000 km.h of severe hypoxia (at > 5,000 m altitude) is probably required to induce skeletal muscle wasting in humans. Journal of applied physiology, 122 (2), 410-410. [BibTeX]
Chaillou, T. , McPeek, A. & Lanner, J. T. (2017). Docetaxel does not impair skeletal muscle force production in a murine model of cancer chemotherapy. Physiological Reports, 5 (11). [BibTeX]
Cheng, A. J. , Willis, S. J. , Zinner, C. , Chaillou, T. , Ivarsson, N. , Ørtenblad, N. , Lanner, J. T. , Holmberg, H. & et al. (2017). Post-exercise recovery of contractile function and endurance in humans and mice is accelerated by heating and slowed by cooling skeletal muscle. Journal of Physiology, 595 (24), 7413-7426. [BibTeX]
Chaillou, T. , Zhang, X. & McCarthy, J. J. (2016). Expression of Muscle-Specific Ribosomal Protein L3-Like Impairs Myotube Growth. Journal of Cellular Physiology, 231 (9), 1894-1902. [BibTeX]
Kirby, T. , Lee, J. , England, J. , Chaillou, T. , Esser, K. & McCarthy, J. (2015). Blunted hypertrophic response in aged skeletal muscle is associated with decreased ribosome biogenesis. Journal of applied physiology, 119 (4), 321-327. [BibTeX]
Chaillou, T. , Jackson, J. , England, J. , Kirby, T. , Richards-White, J. , Esser, K. , Dupont-Versteegden, E. & McCarthy, J. (2015). Identification of a conserved set of upregulated genes in mouse skeletal muscle hypertrophy and regrowth. Journal of applied physiology, 118, 86-97. [BibTeX]
Cheng, A. , Chaillou, T. , Gineste, C. & Schlittler, M. (2015). Intracellular Ca(2+) handling and myofibrillar Ca(2+) sensitivity are defective in single muscle fibres of aged humans. Journal of Physiology, 593 (15), 3237-3238. [BibTeX]
Kirby, T. , Chaillou, T. & McCarthy, J. (2015). The role of microRNAs in skeletal muscle health and disease. Frontiers in Bioscience, 20, 37-77. [BibTeX]
Chaillou, T. , Koulmann, N. , Meunier, A. , Pugnière, P. , McCarthy, J. , Beaudry, M. & Bigard, X. (2014). Ambient hypoxia enhances the loss of muscle mass after extensive injury. Pflügers Archiv: European Journal of Physiology, 466 (3), 587-598. [BibTeX]
Chaillou, T. , Koulmann, N. , Meunier, A. , Chapot, R. , Serrurier, B. , Beaudry, M. & Bigard, X. (2014). Effect of hypoxia exposure on the recovery of skeletal muscle phenotype during regeneration. Molecular and Cellular Biochemistry, 390 (1-2), 31-40. [BibTeX]
Chaillou, T. , Koulmann, N. , Meunier, A. , Malgoyre, A. , Serrurier, B. , Beaudry, M. & Bigard, X. (2013). Effect of hypoxia exposure on the phenotypic adaptation in remodelling skeletal muscle submitted to functional overload. Acta Physiologica, 209 (4), 272-282. [BibTeX]
Chaillou, T. , Koulmann, N. , Simler, N. , Meunier, A. , Serrurier, B. , Chapot, R. , Peinnequin, A. , Beaudry, M. & et al. (2012). Hypoxia transiently affects skeletal muscle hypertrophy in a functional overload model. American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 302, R643-R654. [BibTeX]
Chaillou, T. , Malgoyre, A. , Banzet, S. , Chapot, R. , Koulmann, N. , Pugnière, P. , Beaudry, M. , Bigard, X. & et al. (2011). Pitfalls in target mRNA quantification for real-time quantitative RT-PCR in overload-induced skeletal muscle hypertrophy. Physiological Genomics, 43 (4), 228-235. [BibTeX]
Pugnière, P. , Banzet, S. , Chaillou, T. , Mouret, C. & Peinnequin, A. (2011). Pitfalls of reverse transcription quantitative polymerase chain reaction standardization: Volume-related inhibitors of reverse transcription. Analytical Biochemistry, 415 (2), 151-157. [BibTeX]

Articles, reviews/surveys

Flewwelling, L. D. , Hannaian, S. J. , Cao, V. , Chaillou, T. , Churchward-Venne, T. A. & Cheng, A. J. (2025). What are the potential mechanisms of fatigue-induced skeletal muscle hypertrophy with low-load resistance exercise training?. American Journal of Physiology - Cell Physiology, 328 (3), C1001-C1014. [BibTeX]
Chaillou, T. & Montiel Rojas, D. (2023). Does the blunted stimulation of skeletal muscle protein synthesis by aging in response to mechanical load result from impaired ribosome biogenesis?. Frontiers in aging, 4. [BibTeX]
Chaillou, T. (2019). Ribosome specialization and its potential role in the control of protein translation and skeletal muscle size. Journal of applied physiology, 127 (2), 599-607. [BibTeX]
Chaillou, T. (2018). Skeletal Muscle Fiber Type in Hypoxia: Adaptation to High-Altitude Exposure and Under Conditions of Pathological Hypoxia. Frontiers in Physiology, 9. [BibTeX]
Chaillou, T. (2017). Impaired ribosome biogenesis could contribute to anabolic resistance to strength exercise in the elderly. Journal of Physiology, 595 (5), 1447-1448. [BibTeX]
Chaillou, T. & Lanner, J. T. (2016). Regulation of myogenesis and skeletal muscle regeneration: effects of oxygen levels on satellite cell activity. The FASEB Journal, 30 (12), 3929-3941. [BibTeX]

Conference papers

Chaillou, T. , Treigyte, V. , Eimantas, N. , Venckunas, T. & Brazaitis, M. (2022). Impact of acute and prolonged cooling on skeletal muscle force in young males. Paper presented at 27th ECSS, European Congress of Sport Science, Sevilla, Spain, August 31-September 2, 2022. [BibTeX]
Ghaffar, Q. , Jude, B. , Lanner, J. & Chaillou, T. (2021). Muscle atrophy is associated with activated anabolic and catabolic pathways in a mouse model of rheumatoid arthritis. Paper presented at Scandinavian Physiological Society 2021 meeting, Stockholm, September 2-5, 2021. [BibTeX]
Lanner, J. , Mader, T. , Chaillou, T. , Cheng, A. , Steinz, M. , Zhengye, L. , Rundqvist, H. & Kenne, E. (2019). Running reverses tumor-induced muscle weakness in mice with breast cancer. Paper presented at The Scandinavian Physiological Society Annual Meeting (SPS 2019), Reykjavik, Iceland, August 9-11, 2019. [BibTeX]
Rantala, R. , Kadi, F. & Chaillou, T. (2018). Low temperature affects the morphology and impairs glutamine-induced hypertrophic response in human primary myotubes. Paper presented at Europhysiology, London, UK, September 14-16, 2018. [BibTeX]
Mader, T. , Kenne, E. , Chaillou, T. , Petkovic, M. , Steinz, M. , Liu, Z. , Kalakoutis, M. & Lanner, J. (2018). Metabolic alteration and muscle dysfunction in mice with breast cancer. Paper presented at Europhysiology, London, UK, September 14-16, 2018. [BibTeX]
Cheng, A. , Allodi, I. , Chaillou, T. , Thams, S. , Ivarsson, N. , Schlittler, M. , Lanner, J. , Hedlund, E. & et al. (2017). Increased fatigue resistance and preserved specific force in intact single muscle fibres from the SOD1G93A mouse model of ALS. In: Acta Physiologica. Paper presented at Annual Meeting of the Scandinavian Physiological Society, Oslo, Norway, August 26-28, 2016. (pp. 17-17). Wiley-Blackwell. [BibTeX]
Ferreira, D. , Cheng, A. , Edsgärd, D. , Chaillou, T. , Porsmyr-Palmertz, M. , da Silva, P. , Izadi, M. , Agudelo, L. & et al. (2017). LMCD1B: A novel regulator of skeletal muscle metabolism. Paper presented at Cell Symposia: Exercise Metabolism, Göteborg, Sweden, May 21-23, 2017. [BibTeX]
Chaillou, T. , Hynynen, H. , Ferreira, D. , Pironti, G. , Kenne, E. , Andersson, D. C. , Ruas, J. L. , Tavi, P. & et al. (2016). NDUFA4L2: Connecting metabolic signals and mitochondrial function in cardiac and skeletal muscle. In: Free Radical Biology & Medicine. Paper presented at 23rd Annual Meeting of the Society for Redox Biology and Medicine (SFRBM 2016), San Francisco, USA, November 16-19, 2016. (pp. S186-S186). Elsevier. [BibTeX]
Chaillou, T. , Hynynen, H. , Ferreira, D. , Pironti, G. , Andersson, D. , Ruas, J. , Tavi, P. & Lanner, J. (2016). The mitochondrial NDUFA4L2 protein: a novel modulator of skeletal muscle mass and force. Paper presented at The Scandinavian Physiological Society Annual Meeting, Oslo, Norway, August 26-28, 2016. [BibTeX]
Chaillou, T. , Ivarsson, N. , Mijwel, S. , Cheng, A. , Rundqvist, H. & Lanner, J. (2015). Breast-cancer-induced muscle weakness: benefits of physical exercise to restore muscle function. Paper presented at Excitation-contraction coupling Gordon research Conference, Maine, USA, May 31- June 5, 2015. [BibTeX]
Chaillou, T. , Zhang, X. & McCarthy, J. (2014). Muscle-specific Ribosomal Protein L3-like Inhibits Myotube Growth. Paper presented at 2014 ACSM Annual Meeting, Orlando, USA, May 27-31, 2014. [BibTeX]
Pugnière, P. , Banzet, S. , Chaillou, T. , Mouret, C. & Peinnequin, A. (2012). Volume-related inhibitors standardization for reverse transcription quantitative polymerase chain reaction experiments. Paper presented at Congress of Genomics Research, Boston, USA, April 19-20, 2012. [BibTeX]
Simler, N. , Meunier, A. , Chaillou, T. , Gangloff, K. & Bigard, X. (2011). Activating AMPK signalling in hypothalamus supresses hypoxia-induced hypophagia in rats. Paper presented at Congress of Physiology, Pharmacology, and Therapeutics, Grenoble, France, March 22-24, 2011. [BibTeX]
Malgoyre, A. , Sanchez, H. , Tonini, J. , Serrurier, B. , Prola, A. , Chaillou, T. , Simler, N. & Bigard, X. (2011). Aerobic performance improvment and mitochondrial adaptations after endurance training in hypoxia. In: Acta Physiologica. Paper presented at Scandinavian Physiological Society’s Annual Meeting, Bergen, Norway, August 12-14, 2011. John Wiley & Sons. [BibTeX]
Chaillou, T. , Koulmann, N. , Simler, N. , Meunier, A. , Grégoire, C. , Serrurier, B. , Beaudry, M. & Bigard, X. (2011). Ambient hypoxia enhances the muscle-mass loss after extensive injury. In: The FASEB Journal. Paper presented at Experimental Biology Meeting, Washington DC, USA, April 9-13, 2011. Federation of American Society of Experimental Biology (FASEB). [BibTeX]
Chaillou, T. , Koulmann, N. , Simler, N. , Meunier, A. , Grégoire, C. , Chapot, R. , Serrurier, B. , Beaudry, M. & et al. (2011). Ambient hypoxia enhances the muscle-mass loss after extensive injury. Paper presented at 4th Congress of Myology, Lille, France, May 9-13, 2011. [BibTeX]
Chaillou, T. , Koulmann, N. , Simler, N. , Serrurier, B. , Meunier, A. , Chapot, R. , Peinnequin, A. , Beaudry, M. & et al. (2011). Ambient hypoxia transiently affects muscle growth in a functional overload model in rats. Paper presented at Physiology, Pharmacology and Therapeutics , P2T 2011, Grenoble, France, March 23rd, 2011. [BibTeX]
Chaillou, T. , Koulmann, N. , Beaudry, M. & Bigard, X. (2011). Molecular mechanisms involved in the muscle mass control. Paper presented at 14th Congress of Sports and Physical Activities Researchers Association (ACAPS), Rennes, France, October, 2011. [BibTeX]
Chaillou, T. , Koulmann, N. , Simler, N. , Serrurier, B. , Meunier, A. , Chapot, R. , Peinnequin, A. , Beaudry, M. & et al. (2010). Ambient hypoxia transiently affects muscle growth in a functional overload model in rats. Paper presented at Annual Congress of the European Congress of Sport Science, Antalya, Turkey, 23-26 June 2010. [BibTeX]
Bigard, X. , Chaillou, T. , Sanchez, H. , Malgoyre, A. & Koulmann, N. (2010). How to build high oxidative skeletal muscle?: Interaction between energy stress and muscle growth. Paper presented at 15th Annual European Congress of Sport Science (ECSS 2010), Antalya, Turkey, June 23-26, 2010. [BibTeX]