Christina Karlsson
Befattning: Universitetslektor Organisation: Institutionen för hälsovetenskaperE-post: Y2hyaXN0aW5hLmthcmxzc29uO29ydS5zZQ==
Telefon: 019 303675
Rum: P1326
Om Christina Karlsson
Legitimerad biomedicinsk analytiker och universitetslektor vid Enheten för medicinsk diagnostik, Institutionen för hälsovetenskaper
Doktorsexamen från Örebro universitet 2011 med avhandlingen ”Biomarkers in non-small cell lung carcinoma: methodological aspects and influence of gender, histology and smoking habits on estrogen receptor and epidermal growth factor family receptor signalling”
Undervisning
Christina är sedan 2014 programansvarig för biomedicinska analytikerprogrammet. Hon undervisar inom cellbiologi samt morfologi och morfologiska tekniker i kurser på grund- och avancerad nivå främst inom biomedicinska analytikerprogrammet, men även inom röntgensjuksköterskeprogrammet och sjuksköterskeprogrammet.
Forskning
Christinas forskning inriktar sig främst på biologiska och prognostiska faktorer vid utveckling av tumörsjukdom, och har drivit och medverkat i projekt inom lungcancer, cervixcancer, bröstcancer och endometriecancer. Metoder som används vid dessa analyser innefattar histoteknik, immunhistokemi, FISH och CISH samt bildanalys. Christina är bihandledare till tre doktorander, samt handleder studentuppsatser på både grund- och avancerad nivå.
Publikationer
Artiklar i tidskrifter
- Qvick, A. , Bratulic, S. , Carlsson, J. , Stenmark, B. , Karlsson, C. , Nielsen, J. , Gatto, F. & Helenius, G. (2024). Discriminating Benign from Malignant Lung Diseases Using Plasma Glycosaminoglycans and Cell-Free DNA. International Journal of Molecular Sciences, 25 (18). [BibTeX]
- Lovane, L. , Tulsidás, S. , Carrilho, C. & Karlsson, C. (2024). PD-L1 expression in squamous cervical carcinomas of Mozambican women living with or without HIV. Scientific Reports, 14 (1). [BibTeX]
- Qvick, A. , Andersson, E. , Oldaeus Almerén, A. , Waenerlund, M. , Stenmark, B. , Karlsson, C. , Karlsson, M. & Helenius, G. (2024). Sensitive and Specific Droplet Digital PCR Assays for Circulating Tumor HPV DNA: Development, Validation, and Clinical Application in HPV-Associated Cancers. Molecular Diagnosis & Therapy, 28 (6), 835-845. [BibTeX]
- Lovane, L. , Carrilho, C. & Karlsson, C. (2024). Tissue microarray validation in cervical carcinoma studies: A methodological approach. Histology and Histopathology. [BibTeX]
- Hurtsén, A. S. , McGreevy, D. T. , Karlsson, C. , Frostell, C. G. , Hörer, T. M. & Nilsson, K. F. (2023). A randomized porcine study of hemorrhagic shock comparing end-tidal carbon dioxide targeted and proximal systolic blood pressure targeted partial resuscitative endovascular balloon occlusion of the aorta in the mitigation of metabolic injury. Intensive Care Medicine Experimental, 11 (1). [BibTeX]
- Wikström, M. B. , Smårs, S. M. , Karlsson, C. , Hurtsén, A. S. , Hörer, T. M. & Nilsson, K. F. (2021). A randomized porcine study of the hemodynamic and metabolic effects of combined endovascular occlusion of the vena cava and the aorta in normovolemia and in hemorrhagic shock. Journal of Trauma and Acute Care Surgery, 90 (5), 817-826. [BibTeX]
- Gebregzabher, E. , Seifu, D. , Tigneh, W. , Bokretsion, Y. , Bekele, A. , Abebe, M. , Lillsunde-Larsson, G. , Karlsson, C. & et al. (2021). Detection of High- and Low-Risk HPV DNA in Archived Breast Carcinoma Tissues from Ethiopian Women. International Journal of Breast Cancer, 2021. [BibTeX]
- Qvick, A. , Stenmark, B. , Carlsson, J. , Isaksson, J. , Karlsson, C. & Helenius, G. (2021). Liquid biopsy as an option for predictive testing and prognosis in patients with lung cancer. Molecular Medicine, 27 (1). [BibTeX]
- Hadgu, E. , Seifu, D. , Tigneh, W. , Bokretsion, Y. , Bekele, A. , Abebe, M. , Sollie, T. , Karlsson, C. & et al. (2020). Distribution and characteristics of androgen receptor (AR) in breast cancer among women in Addis Ababa, Ethiopia: A cross sectional study. PLOS ONE, 15 (5). [BibTeX]
- Sadeghi, M. , Dogan, E. M. , Karlsson, C. , Jansson, K. , Seilitz, J. , Skoog, P. , Hörer, T. M. & Nilsson, K. F. (2020). Total resuscitative endovascular balloon occlusion of the aorta causes inflammatory activation and organ damage within 30 minutes of occlusion in normovolemic pigs. BMC Surgery, 20 (1). [BibTeX]
- Santti, K. , Ihalainen, H. , Rönty, M. , Karlsson, C. , Haglund, C. , Sampo, M. , Tarkkanen, M. & Blomqvist, C. (2019). Estrogen receptor beta expression correlates with proliferation in desmoid tumors. Journal of Surgical Oncology, 119 (7), 873-879. [BibTeX]
- Hadgu, E. , Seifu, D. , Tigneh, W. , Bokretsion, Y. , Bekele, A. , Abebe, M. , Sollie, T. , Merajver, S. D. & et al. (2018). Breast cancer in Ethiopia: evidence for geographic difference in the distribution of molecular subtypes in Africa. BMC Women's Health, 18 (1). [BibTeX]
- Santti, K. , Ihalainen, H. , Rönty, M. , Böhling, T. , Karlsson, C. , Haglund, C. , Tarkkanen, M. & Blomqvist, C. (2018). High cyclin A expression, but not Ki67, is associated with early recurrence in desmoid tumors. Journal of Surgical Oncology, 118 (1), 192-198. [BibTeX]
- Mattsson, J. S. M. , Brunnström, H. , Jabs, V. , Edlund, K. , Jirström, K. , Mindus, S. , la Fleur, L. , Pontén, F. & et al. (2016). Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer. BMC Cancer, 16 (1). [BibTeX]
- Mattsson, J. S. M. , Bergman, B. , Grinberg, M. , Edlund, K. , Marincevic, M. , Jirström, K. , Pontén, F. , Hengstler, J. G. & et al. (2015). Prognostic impact of COX-2 in non-small cell lung cancer: a comprehensive compartment-specific evaluation of tumor and stromal cell expression. Cancer Letters, 356 (2), 837-845. [BibTeX]
- Stjernström, A. , Karlsson, C. , Fernandez, O. J. , Söderkvist, P. , Karlsson, M. G. & Thunell, L. K. (2014). Alterations of INPP4B, PIK3CA and pAkt of the PI3K pathway are associated with squamous cell carcinoma of the lung. Cancer Medicine, 3 (2), 337-348. [BibTeX]
- Botling, J. , Edlund, K. , Lohr, M. , Hellwig, B. , Holmberg, L. , Lambe, M. G. , Berglund, A. , Ekman, S. & et al. (2013). Biomarker Discovery in Non-Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation. Clinical Cancer Research, 19 (1), 194-204. [BibTeX]
- Karlsson, C. , Helenius, G. , Fernandes, O. & Karlsson, M. G. (2012). Oestrogen receptor ss in NSCLC: prevalence, proliferative influence, prognostic impact and smoking. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), 120 (6), 451-458. [BibTeX]
- Karlsson, C. & Karlsson, M. G. (2011). Effects of long-term storage on the detection of proteins, DNA, and mRNA in tissue microarray slides. Journal of Histochemistry and Cytochemistry, 59 (12), 1113-1121. [BibTeX]
- Karlsson, C. , Bodin, L. , Piehl-Aulin, K. & Karlsson, M. G. (2009). Tissue microarray validation: a methodologic study with special reference to lung cancer. Cancer Epidemiology, Biomarkers and Prevention, 18 (7), 2014-2021. [BibTeX]
- Hellquist, H. B. , Karlsson, M. G. , Karlsson, C. , Viale, G. , Dell'Orto, P. , Davidsson, Å. & Olofsson, J. (1996). Bcl-2 immunoreactivity in salivary gland neoplasms is unrelated to the expression of mRNA for natural killer cell stimulatory cytokines interleukin (IL)-2 and IL-12. Virchows Archiv, 429 (2-3), 149-158. [BibTeX]
Doktorsavhandlingar, sammanläggningar
- Karlsson, C. (2011). Biomarkers in non-small cell lung carcinoma: methodological aspects and influence of gender, histology and smoking habits on estrogen receptor and epidermal growth factor family receptor signalling. (Doctoral dissertation). (Sammanläggning) Örebro: Örebro universitet. [BibTeX]
Konferensbidrag
- Bekele, M. , Jibril, A. , Seifu, D. , Abebe, M. , Bekele, A. , Tigneh, W. , Bokretsion, Y. , Karlsson, C. & et al. (2020). Tumor and immune cell profiling in breast cancer using highly multiplexed imaging mass cytometry single-cell technology demonstrates tumor heterogeneity and immune phenotypic abnormality in Ethiopian women. I: Cancer Research. Konferensbidrag vid AACR Virtual Special Conference on Tumor Heterogeneity - From Single Cells to Clinical Impact, September 17-18, 2020, Electronic Network. American Association for Cancer Research. [BibTeX]
- Mattsson, J. S. M. , Svensson, M. A. , Hallström, B. , Koyi, H. , Branden, E. , Brunnström, H. , Edlund, K. , Ekman, S. & et al. (2015). ALK Rearrangements in Non-Small Cell Lung Cancer: Comprehensive Integration of Genomic, Gene Expression and Protein Analysis. I: Journal of Thoracic Oncology. Elsevier. [BibTeX]
Manuskript
- Lovane, L. , Lillsunde-Larsson, G. , Tulsidás, S. , Carrilho, C. , Andersson, S. & Karlsson, C. Endocervical adenocarcinomas and HPV genotyping in an HIV endemic milieu : a retrospective study. [BibTeX]
- Lovane, L. , Lillsunde-Larsson, G. , Tulsidas, S. , Carrilho, C. , Andersson, S. & Karlsson, C. HPV genotypes in cervical squamous cell carcinoma in an HIV endemic milieu : Mozambique. [BibTeX]
- Qvick, A. , Adolfsson, E. , Tornéus, L. , Lindqvist, C. M. , Carlsson, J. , Stenmark, B. , Karlsson, C. & Helenius, G. Methylation patterns in cell-free DNA for pan-cancer detection. [BibTeX]