Stroke and other CNS injuries

The research group Stroke and other CNS-injuries work with research on different aspects of stroke and other injuries in the central nervous system. The focus is on clinical research and registry based studies but we are also involved in clinical studies. There is an extensive collaboration nationally but also internationally.

Some of the projects we are involved in now are:

• Stroke epidemiology, etiology, and risk factors
• Sex and gender differences in stroke
• Reperfusion treatment in stroke, effect of EVT
• Secondary prevention and follow up after stroke
• Treatment of poststroke epilepsy
• Antiepileptic medication utilisation after stroke PCI and the risk of stroke
• How the Covid pandemic affectet incidens and search patterns for stroke
• Dementia and stroke
• Cognitive and emotional failure after stroke
• Spinal cord injuries and reproduction in women
• Consequences of mild traumatic brain injury (TBI)
• Biomarkers of TBI
• Multimodal neuromonitoring

Ongoing projects
Cerebral hemodynamics and vascular risk factors in adults with cognitive symptoms
in cooperation with Uppsala University and Vestre Viken Hospital Trust, Norway.
PhD-student: David Fresnais, MD
Senior researcher: Brynjar Fure
Publications:
Fresnais D et al. Dement Geriatr Cogn Disord. 2021;50(4):305-317

Stroke in older people
in cooperation with Akershus University Hospital, Norway.
PhD-student: Johan Sanner, MD.
Senior researcher: Brynjar Fure, Mia von Euler, Jakob Ström

Women with spinal cord injury
in collaboration with researchers at Karolinska Institute and Spinalis.
PhD-student Molly Khalili, MD
Senior researcher: Mia von Euler
Publications:
Khalili M et al. Acta Obstet Gynecol Scand. 2022 Nov;101(11):1282-1290.

ALS in Sweden – epidemiology, phenotype and genotype
in collaboration with researchers at Karolinska Institute.
PhD-student Sofia Imrell, MD
Senior researcher: Mia von Euler

COVID-19 and need of neurological care
in collaboration with researchers at Riksstroke.
PhD-student Avin Tofiq
Senior researcher: Mia von Euler and Jakob Ström
Publications:
Tofiq A et al. Disabil Rehabil. 2023 Apr 20;1-10.

Antithrombotic treatment and its effects on intracranial hemorrhages
PhD-student (to be registered) Matthias Tallroth
Senior researcher: Mia von Euler, Andras Buki, Jakob Ström

Sex differences in stroke epidemiology and stroke care
in collaboration with researchers at mainly Umeå university
Senior researcher: Mia von Euler
Publications:

• Eriksson M et al. J Am Heart Assoc. 2023 Feb 7;12(3):e028222.
• Norman K et al. Front Neurol. 2022 Feb 14;13:793181. 
• Eriksson M et al. Stroke. 2021 Oct;52(10):3233-3242. 

Thrombectomy – register based analyses
in collaboration with researchers at mainly Lund university
Senior researcher: Mia von Euler
Publications:

• Ulberg T et al. Neurointerv Surg. 2023 Apr;15(4):330-335. 
• Ulberg T et al. Interv Neuroradiol. 2023 Feb;29(1):94-101.
• Wasselius J et al. J Intern Med. 2022 Mar;291(3):303-316.

NIHSS 0 in acute stroke – is it true?
in collaboration with Riksstroke, mainly researcher at Lund University
Senior researcher: Mia von Euler

AF SPICE – atrial fibrillation screening post ischemic cerebrovascular events
in collaboration with researchers across Sweden and Riksstroke.
Senior researcher: Mia von Euler and Jakob Ström

Inflammatory Biomarkers in Stroke
PhD-student: Björn Röyter
Senior researcher: Jakob Ström

Post stroke fatigue and its relation to physical activity
PhD-student: Maria Svedjebrant
Senior researcher: Jakob Ström

Traumatic Brain Injury (TBI): Aids in Management in the Emergency Department
Senior researcher: Shahin Mohseni, Andras Buki
PhD-student: Dhanisha Trivedi

The Örebro mTBI Register: characterization of mild traumatic brain injury with focus on patients with adverse outcome
Senior researcher: Andras Buki
PhD-student: Dhanisha Trivedi