Robert Kruse

Artiklar i tidskrifter

• Salomon, B. , Sudhakar, P. , Bergemalm, D. , Andersson, E. , Grännö, O. , Carlson, M. , Hedin, C. R. H. , Söderholm, J. D. & et al. (2024). Characterisation of IBD heterogeneity using serum proteomics: A multicentre study.  Journal of Crohn's & Colitis. [BibTeX]
• Salihovic, S. , Eklund, D. , Kruse, R. , Wallgren, U. , Hyötyläinen, T. , Särndahl, E. & Kurland, L. (2024). Exploring the circulating metabolome of sepsis: metabolomic and lipidomic profiles sampled in the ambulance.  Metabolomics, 20 (5). [BibTeX]
• Ling Lundström, M. , Peterson, C. , Hedin, C. R. H. , Bergemalm, D. , Lampinen, M. , Magnusson, M. K. , Keita, Å. V. , Kruse, R. & et al. (2024). Faecal biomarkers for diagnosis and prediction of disease course in treatment-naïve patients with IBD.  Alimentary Pharmacology and Therapeutics, 60 (6), 765-777. [BibTeX]
• Salihovic, S. , Nyström, N. , Mathisen, C. B. , Kruse, R. , Olbjørn, C. , Andersen, S. , Noble, A. J. , Dorn-Rasmussen, M. & et al. (2024). Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease.  Nature Communications, 15 (1). [BibTeX]
• Östling, H. , Lodefalk, M. , Bergman, L. , Zaigham, M. , Andersson, O. , Carlsson, Y. , Veje, M. , Wikström, A. & et al. (2024). Inflammatory and cardiovascular markers in placenta following SARS-CoV-2 infection during pregnancy: A Swedish prospective cohort study.  Placenta, 158, 78-88. [BibTeX]
• Grännö, O. , Bergemalm, D. , Salomon, B. , Lindqvist, C. M. , Hedin, C. R. H. , Carlson, M. , Dannenberg, K. , Andersson, E. & et al. (2024). Preclinical protein signatures of Crohn's disease and ulcerative colitis: A nested case-control study within large population-based cohorts.  Gastroenterology. [BibTeX]
• Lundström, M. L. , Peterson, C. , Lampinen, M. , Hedin, C. R. H. , Keita, Å. V. , Kruse, R. , Magnusson, M. K. , Lindqvist, C. M. & et al. (2023). Fecal Biomarkers of Neutrophil and Eosinophil Origin Reflect the Response to Biological Therapy and Corticosteroids in Patients With Inflammatory Bowel Disease.  Clinical and Translational Gastroenterology, 14 (8). [BibTeX]
• Scherbak, N. N. , Kruse, R. , Nyström, T. & Jendle, J. (2023). Glimepiride Compared to Liraglutide Increases Plasma Levels of miR-206, miR-182-5p, and miR-766-3p in Type 2 Diabetes Mellitus: A Randomized Controlled Trial.  Diabetes & metabolism journal, 47 (5), 668-681. [BibTeX]
• Scherbak, N. , Kruse, R. , Nyström, T. & Jendle, J. (2023). Glimepiride Compared to Liraglutide Increases Plasma Levels of miR-206, miR-182-5p, and miR-766-3p in Type 2 Diabetes Mellitus: A Randomized Controlled Trial (Diabetes Metab J 2023;47:668-81).  Diabetes & metabolism journal, 47 (6), 882-883. [BibTeX]
• Nikaein, N. , Tuerxun, K. , Cedersund, G. , Eklund, D. , Kruse, R. , Särndahl, E. , Nånberg, E. , Thonig, A. & et al. (2023). Mathematical models disentangle the role of IL-10 feedbacks in human monocytes upon proinflammatory activation.  Journal of Biological Chemistry, 299 (10). [BibTeX]
• Tuerxun, K. , Eklund, D. , Wallgren, U. , Dannenberg, K. , Repsilber, D. , Kruse, R. , Särndahl, E. & Kurland, L. (2023). Predicting sepsis using a combination of clinical information and molecular immune markers sampled in the ambulance.  Scientific Reports, 13 (1). [BibTeX]
• Chelslín, F. , Lodefalk, M. & Kruse, R. (2023). Smoking during pregnancy is associated with the placental proteome.  Reproductive Toxicology, 119. [BibTeX]
• Tuerxun, K. , Midtbö, K. , Särndahl, E. , Vorontsov, E. , Karlsson, R. , Persson, A. , Kruse, R. , Eklund, D. & et al. (2022). Cytokine responses to LPS in reprogrammed monocytes are associated with the transcription factor PU.1.  Journal of Leukocyte Biology, 112 (4), 679-692. [BibTeX]
• Juzenas, S. , Hübenthal, M. , Lindqvist, C. M. , Kruse, R. , Steiert, T. A. , Degenhardt, F. , Schulte, D. , Nikolaus, S. & et al. (2022). Detailed transcriptional landscape of peripheral blood points to increased neutrophil activation in treatment-naïve inflammatory bowel disease.  Journal of Crohn's & Colitis, 16 (7), 1097-1109. [BibTeX]
• Moraes Holst, L. , Halfvarson, J. , Carlson, M. , Hedin, C. , Kruse, R. , Lindqvist, C. M. , Bergemalm, D. , Almér, S. & et al. (2022). Downregulated Mucosal Autophagy, Alpha Kinase-1 and IL-17 Signaling Pathways in Active and Quiescent Ulcerative Colitis.  Clinical and Experimental Gastroenterology, 15, 129-144. [BibTeX]
• Östling, H. , Lodefalk, M. , Backman, H. & Kruse, R. (2022). Global microRNA and protein expression in human term placenta.  Frontiers in Medicine, 9. [BibTeX]
• Persson, K. , Petersson, U. , Johansson, C. , Demirel, I. & Kruse, R. (2022). Transcriptional alterations in bladder epithelial cells in response to infection with different morphological states of uropathogenic Escherichia coli.  Scientific Reports, 12 (1). [BibTeX]
• Chelslín, F. , Kruse, R. , Östling, H. & Lodefalk, M. (2021). Differential microRNA expression in placentas of small-for-gestational age neonates with and without exposure to poor maternal gestational weight gain.  Journal of Perinatal Medicine, 49 (5), 632-635. [BibTeX]
• Berg von Linde, M. , Johansson, K. , Kruse, R. , Helenius, G. , Samano, N. , Friberg, Ö. , Frøbert, A. M. & Fröbert, O. (2021). Expression of Paracrine Effectors in Human Adipose-Derived Mesenchymal Stem Cells Treated With Plasma From Brown Bears (Ursus arctos).  Clinical and Translational Science, 14 (1), 317-325. [BibTeX]
• Demirel, I. , Persson, A. , Brauner, A. , Särndahl, E. , Kruse, R. & Persson, K. (2020). Activation of NLRP3 by uropathogenic Escherichia coli is associated with IL-1β release and regulation of antimicrobial properties in human neutrophils.  Scientific Reports, 10 (1). [BibTeX]
• Serhan, C. N. , Gupta, S. K. , Perretti, M. , Godson, C. , Brennan, E. , Li, Y. , Soehnlein, O. , Shimizu, T. & et al. (2020). The Atlas of Inflammation Resolution (AIR).  Molecular Aspects of Medicine, 74. [BibTeX]
• Östling, H. , Kruse, R. , Helenius, G. & Lodefalk, M. (2019). Placental expression of microRNAs in infants born small for gestational age.  Placenta, 81, 46-53. [BibTeX]
• Demirel, I. , Persson, A. , Brauner, A. , Särndahl, E. , Kruse, R. & Persson, K. (2018). Activation of the NLRP3 Inflammasome Pathway by Uropathogenic Escherichia coli Is Virulence Factor-Dependent and Influences Colonization of Bladder Epithelial Cells.  Frontiers in Cellular and Infection Microbiology, 8. [BibTeX]
• Bergemalm, D. , Kruse, R. , Sapnara, M. , Halfvarson, J. & Hultgren Hörnquist, E. (2017). Elevated fecal peptidase D at onset of colitis in Galphai2(-/-) mice, a mouse model of IBD.  PLOS ONE, 12 (3). [BibTeX]
• Bang, C. S. , Demirel, I. , Kruse, R. & Persson, K. (2017). Global gene expression profiling and antibiotic susceptibility after repeated exposure to the carbon monoxide-releasing molecule-2 (CORM-2) in multidrug-resistant ESBL-producing uropathogenic Escherichia coli.  PLOS ONE, 12 (6). [BibTeX]
• Andersson, E. , Bergemalm, D. , Kruse, R. , Neumann, G. , D'Amato, M. , Repsilber, D. & Halfvarson, J. (2017). Subphenotypes of inflammatory bowel disease are characterized by specific serum protein profiles.  PLOS ONE, 12 (10). [BibTeX]
• Demirel, I. , Rangel, I. , Petersson, U. , Persson, K. & Kruse, R. (2017). Transcriptional Alterations of Virulence-Associated Genes in Extended Spectrum Beta-Lactamase (ESBL)-Producing Uropathogenic Escherichia coli during Morphologic Transitions Induced by Ineffective Antibiotics.  Frontiers in Microbiology, 8. [BibTeX]
• Vumma, R. , Bang, C. S. , Kruse, R. , Johansson, K. & Persson, K. (2016). Antibacterial effects of nitric oxide on uropathogenic Escherichia coli during bladder epithelial cell colonization-a comparison with nitrofurantoin.  Journal of antibiotics (Tokyo. 1968), 69 (3), 183-186. [BibTeX]
• Sahlberg Bang, C. , Kruse, R. , Johansson, K. & Persson, K. (2016). Carbon monoxide releasing molecule-2 (CORM-2) inhibits growth of multidrug-resistant uropathogenic Escherichia coli in biofilm and following host cell colonization.  BMC Microbiology, 16 (1). [BibTeX]
• Demirel, I. , Kruse, R. , Önnberg, A. & Persson, K. (2015). Ceftibuten-induced filamentation of extended spectrum beta lactamase (ESBL)-producing uropathogenic Escherichia coli alters host cell responses during an in vitro infection.  Microbial Pathogenesis, 78, 52-62. [BibTeX]
• Kruse, R. , Demirel, I. , Säve, S. & Persson, K. (2014). IL-8 and global gene expression analysis define a key role of ATP in renal epithelial cell responses induced by uropathogenic bacteria.  Purinergic Signalling Purinergic Signalling, 10 (3), 499-508. [BibTeX]
• Bang, C. S. , Kruse, R. , Demirel, I. , Önnberg, A. , Söderquist, B. & Persson, K. (2014). Multiresistant uropathogenic extended-spectrum β-lactamase (ESBL)-producing Escherichia coli are susceptible to the carbon monoxide releasing molecule-2 (CORM-2)..  Microbial Pathogenesis, 66, 29-35. [BibTeX]
• Demirel, I. , Säve, S. , Kruse, R. & Persson, K. (2013). Expression of suppressor of cytokine signalling 3 (SOCS3) in human bladder epithelial cells infected with uropathogenic Escherichia coli.  Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), 121 (2), 158-167. [BibTeX]
• Zhang, B. , Elmabsout, A. A. , Khalaf, H. , Basic, V. T. , Jayaprakash, K. , Kruse, R. , Bengtsson, T. & Sirsjö, A. (2013). The periodontal pathogen Porphyromonas gingivalis changes the gene expression in vascular smooth muscle cells involving the TGFbeta/Notch signalling pathway and increased cell proliferation.  BMC Genomics, 14, 770. [BibTeX]
• Kruse, R. , Säve, S. & Persson, K. (2012). Adenosine triphosphate induced P2Y(2) receptor activation induces proinflammatory cytokine release in uroepithelial cells.  Journal of Urology, 188 (6), 2419-2425. [BibTeX]
• Jensen-Waern, M. , Kruse, R. & Lundgren, T. (2012). Oral immunosuppressive medication for growing pigs in transplantation studies.  Laboratory Animals, 46 (2), 148-151. [BibTeX]
• Kruse, R. , Dutta, P. C. & Morrell, J. M. (2011). Colloid centrifugation removes seminal plasma and cholesterol from boar spermatozoa.  Reproduction, Fertility and Development, 23 (7), 858-65. [BibTeX]
• Kruse, R. , Essén-Gustavsson, B. , Fossum, C. & Jensen-Waern, M. (2008). Blood concentrations of the cytokines IL-1beta, IL-6, IL-10, TNF-alpha and IFN-gamma during experimentally induced swine dysentery.  Acta Veterinaria Scandinavica, 50. [BibTeX]

Konferensbidrag

• Selin, K. A. , Repsilber, D. , Strid, H. , Lindqvist, C. M. , Kruse, R. , Magnusson, M. K. , Öhman, L. , Carlson, M. & et al. (2024). Depressive symptoms in ulcerative colitis and Crohn's disease - differences in improvement at 1 year follow-up. I:  Journal of Crohn's & Colitis. Konferensbidrag vid 19th Congress of ECCO, Stockholm, Sweden, February 21-24, 2024. (ss. I1985-I1985). Oxford University Press. [BibTeX]
• Grännö, O. , Salomon, B. , Lindqvist, C. M. , Hedin, C. R. H. , Carlson, M. , Dannenberg, K. , Andersson, E. , Söderholm, J. D. & et al. (2024). Preclinical protein signatures in blood predict Crohn's disease and Ulcerative colitis several years before the diagnosis. I:  Journal of Crohn's & Colitis. Konferensbidrag vid 9th Congress of ECCO, Stockholm, Sweden, February 21-24, 2024. (ss. I660-I661). Oxford University Press. [BibTeX]
• Salomon, B. , Carlson, M. , Bergemalm, D. , Hedin, C. R. H. , Söderholm, J. D. , Keita, Å. V. , Carsten, A. , Grip, O. & et al. (2024). Prognostic potential of mucosal proteins in Ulcerative Colitis. I:  Journal of Crohn's & Colitis. Konferensbidrag vid 16th Congress of ECCO - European Crohn’s and Colitis Organisation (ECCO'21), (Virtual congress), July 2-3, 8-10, 2021. (ss. I544-I545). Oxford University Press. [BibTeX]
• Mathisen, C. B. , Nyström, N. , Bazov, I. , Andersen, S. , Olbjørn, C. , Perminow, G. , Kristensen, V. A. , Opheim, R. & et al. (2023). A novel diagnostic serum protein signature for paediatric Inflammatory Bowel Disease: A discovery and validation study in two independent inception cohorts. I:  Journal of Crohn's & Colitis. Konferensbidrag vid 8th Congress of ECCO Copenhagen, Denmark, March 1-4, 2023. (ss. I71-I73). Oxford University Press. [BibTeX]
• Bazov, I. , Kruse, R. , Bergemalm, D. , Eriksson, C. , Hedin, C. R. , Carlson, M. , van Nieuwenhoven, M. , Keita, Å. V. & et al. (2023). A novel serum protein signature as biomarker for Inflammatory Bowel Disease: A diagnostic performance and prediction modelling study using data from two independent inception cohorts. I:  Journal of Crohn's & Colitis. Konferensbidrag vid 18th Congress of ECCO Copenhagen, Denmark, March 1-4, 2023. (ss. I314-I315). Oxford University Press. [BibTeX]
• Salihovic, S. , Nyström, N. , Mathisen, C. B. , Andersen, S. , Olbjørn, C. , Perminow, G. , Opheim, R. , Detlie, T. E. & et al. (2023). Identification and validation of a lipidomic signature as a novel diagnostic biomarker of paediatric Inflammatory Bowel Disease. I:  Journal of Crohn's & Colitis. Oxford University Press. [BibTeX]
• Östling, H. , Lodefalk, M. , Backman, H. & Kruse, R. (2022). Global microRNA and protein expression in human term placenta may improve our understanding of fetal growth. I:  Hormone Research in Paediatrics. Konferensbidrag vid 60th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE), Rome, Italy, September 15–17, 2022. (ss. 247-247). S. Karger. [BibTeX]
• Östling, H. , Lodefalk, M. , Backman, H. & Kruse, R. (2022). Global microRNA and protein expression in humanterm placenta may improve our understandingof fetal growth. I:  Hormone Research in Paediatrics. Konferensbidrag vid 60th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE), Rome, Italy, September 15–17, 2022. (ss. 247-247). S. Karger. [BibTeX]
• Welander, E. , Åström, M. , Enonge Fotabe, L. , Kardeby, C. , Tina, E. , Elgbratt, K. , Pourlotfi, A. , Abawi, A. & et al. (2018). Integrated analysis indicates reciprocal immune response dysregulations between bone marrow multipotent stromal cells and granulocytes at the mRNA but not at the protein level in myelofibrosis. Konferensbidrag vid Fortbildningsdagar i hematologi, Umeå, 3-5 Oktober, 2018. [BibTeX]
• Östling, H. , Kruse, R. , Helenius, G. & Lodefalk, M. (2017). Infants born small-for-gestational age have different placental expression of microRNAs. I:  Hormone Research in Paediatrics. Konferensbidrag vid 10th International Meeting of Pediatric Endocrinology, Washington D.C., USA, September 14-17, 2017. (ss. 100-101). S. Karger. [BibTeX]
• Andersson, E. , Bergemalm, D. , Kruse, R. , D'Amato, M. , Repsilber, D. & Halfvarson, J. (2016). Inflammatory biomarkers in serum discriminate Crohn's disease and ulcerative colitis from healthy controls. I:  Journal of Crohn's & Colitis. Oxford University Press. [BibTeX]

Manuskript

• Demirel, I. , Kruse, R. , Önnberg, A. & Persson, K. Antibiotic-induced filamentation of extended spectrum beta lactamase (ESBL)-producing uropathogenic E. coli alters host cell responses during an in vitro infection. [BibTeX]
• Visuri, I. , Dannenberg, K. , Salomon, B. , Ling Lundström, M. , Bergemalm, D. , Eriksson, C. , Lindqvist, C. M. , Keita, Å. V. & et al. Correlations of clinical characteristics and serum proteins with drug levels : A multicentre cohort study of patients with inflammatory bowel disease starting biologics. [BibTeX]
• Göthlin Eremo, A. , Tina, E. , Kruse, R. , Fransén, K. , Wegman, P. , Repsilber, D. , Montgomery, S. , Sollie, T. & et al. Gene expression profiles in breast tumors from tamoxifen treated patients with and without distant recurrence. [BibTeX]
• Sahlberg Bang, C. , Kruse, R. & Persson, K. Global gene expression profiling and antibiotic susceptibility after repeated exposure to the carbon monoxide-releasing molecule-2 (CORM-2) in multidrug-resistant ESBL-producing uropathogenic Escherichia coli. [BibTeX]
• Carstens, A. , Björkqvist, O. , Lindqvist, C. M. , Rangel, I. , Repsilber, D. , Eriksson, C. , Bergemalm, D. , Bresso, F. & et al. Gut microbiota associated with treatment outcome to biological treatment in inflammatory bowel disease. [BibTeX]
• Folkesson, M. , Kruse, R. & Kadi, F. HSP27 is not mandatory for the hypertrophy of human skeletal muscle cells. [BibTeX]
• Tuerxun, K. , Kurland, L. , Särndahl, E. , Wallgren, U. , Eklund, D. & Kruse, R. Inflammatory imbalance in ambulance patients is associated with sepsis and septic shock. [BibTeX]