Research projects
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Gene variants of the NLRP3 inflammasome in Neisseria meningitidis-induced severe infection
This project investigates how the host-microbe interplay determines why some individuals develop a severe, sometimes fatal, inflammatory response in reaction...
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Gene variants of the NLRP3 inflammasome in Staphylococcus aureus-induced severe infection
This project investigates how the host-microbe interplay determines why some individuals respond with severe, life-threatening symptoms upon S. aureus...
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Genetic variations in genes associated with inflammation and predisposition for altered biomarker profiles
Atherosclerosis is one of the underlying factors for cardiovascular diseases and is characterized by chronic inflammatory processes in the atherosclerotic...
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Genome, genome regulation and expression
In year 2006 I established the Swedish National Programme for genetics in IBD (SNP-IBD) in collaboration with Prof. Johan Söderholm, Linköping University...
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Grade III-V Isthmic Spondylolisthesis in Children and Teenagers. A Long-Term Follow-Up of In Situ Fusion
This mixed prospective and retrospective study will report the outcome three decades after uninstrumented in situ fusion for high-grade isthmic spondylolisth...
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Human exposure to per- and polyfluoroalkyl substances? Role of the gut microbiome and bile acid metabolism in mediating impact (PFASgut)
The theme of the project is the assessment of the health impacts of exposure to per- and polyfluoroalkyl substances (PFAS), and the elucidation of the effect...
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Hur påverkar fibrer mag- och tarmbarriären hos äldre personer
Through experimental studies using the Ussing chamber technique, we have been able to show that beta-glucan from yeast has the ability to prevent mast...
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Hypoglycaemia reduction in subpopulations with type 1 or type 2 diabetes after switching to insulin degludec from other basal insulins: a multi-national, multi-centre, prospective, observational study (ReFLeCT).
Information on available in Swedish
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Identification of dietary fibres that promotes butyrate production
Butyrate-producing bacteria have recently gained attention as an important bacterial group within the human gut microbiota, as they are important for a healt...
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Ikaria Healthy Ageing
Presentation The island of Ikaria in the Aegean Sea is characterized by the unusually high number of inhabitants reaches an age of 90 years, and furthermore...