Effects of multi-modal non-pharmacological treatment in adult patients with ADHD - A randomised controlled study

ADHD is characterized by difficulty to focus and sustain attention and extert top-down control over behaviour. Roughly 3% of the adult population meets criteria for ADHD. Treatment is multimodal with a combination of pharmacological and non-pharmacological interventions. Psychostimulants (CS) are the mainstay of treatment, however their longterm efficacy and adverse effects is not fully known. Roughly 30% of patients also fail to respond to pharmacological treatment.

The main goal of our study is to develop new non-pharmacological treatment option for adult patients with ADHD. START is a randomized controlled trial that will evaluate the effects of a 12-week long regular physical exercise, given with or without cognitive intervention. Effect will be measured before and after intervention, as well as 6 and 12 months post intervention, using rating scales, cognitive and physical tests, magnetic resonance imaging and blood samples.