Comorbid Conditions of Attention deficit / hyperactive disorders (CoCA)

The aim of this project is to document the comorbidity patterns of ADHD with substance use disorders, obesity, and anxiety/mood disorders across the lifespan and to determine societal impact. While all of the disorders studied are common, precise estimates of their comorbid prevalence and socioeconomic impact are unknown and much needed. Patterns of comorbidity of ADHD with each of the four conditions will be documented, per lifespan period, and by sex, and evaluated in terms of costs. We will determine how comorbid patterns are transmitted across generations. 

While all of the disorders studied are common, precise estimates of their comorbid prevalence and their socioeconomic impact are needed. In addition, patterns of comorbidity across the lifespan and their stability across generations are not well documented. Nor have gender effects on impact and persistence been described. This project use very large population samples from several countries and datasets from German health insurances to study the following four aims:

Aim 1: Determine medical costs and work loss by performing health-economic analyses and document the pattern of costs stratified by comorbidity type and sex,

Aim 2: Investigate patterns of comorbidity across the lifespan,

Aim 3: Describe sex-specific patterns of comorbidity,

Aim 4: Document multigenerational transmission patterns of comorbidity.