Adrenergic signalling in cancer progression

There is increasing evidence that neuroendocrine signalling may play a role in cancer progression. We are exploring the role of b-adrenergic signalling in cancer progression using several existing data sources, including nationwide population registers and two well-characterized prostate cancer patient cohorts for which detailed data are available. Including studies of gene expression patterns in individual tumours to population level data analyses on prescribed medication use among cancer patients our data, we hope to advance the understanding of b-adrenergic signalling in cancer pathogenesis and the potential role of b-adrenergic receptors as targets for therapeutic intervention.