Matej Oresic
Matej Oresic Position: Professor School/office: School of Medical SciencesEmail: bWF0ZWoub3Jlc2ljO29ydS5zZQ==
Phone: +46 19 302137
Room: X2201
- Man-Technology-Environment research centre (MTM)
- Nutrition-Gut-Brain Interactions Research Centre (NGBI)
-
Responsive Nutrition Research Centre
About Matej Oresic
Matej Orešič holds a PhD in biophysics from Cornell University. He is a professor in medicine with a specialization in systems medicine at Örebro Universitry and group leader in systems medicine at the Turku Centre for Biotechnology, University of Turku. Prof. Orešič’s main research areas include exposomics and metabolomics applications in biomedical research and systems medicine. He is particularly interested in the identification of environmental exposures (exposome) and disease processes associated with different metabolic phenotypes and the underlying mechanisms linking these processes with the development of specific disorders or their co-morbidities. Prof. Orešič has also initiated the popular MZmine open source project, leading to popular software for metabolomics data processing. He currently coordinates European collaborative project ’Inflammation in human early life: targeting impacts on life-course health’ – INITIALISE (https://initialise-project.eu/).
Previosuly, Prof. Orešič was principal investigator at Steno Diabetes Center (Gentofte, Denmark), research professor at VTT Technical Research Centre of Finland (Espoo, Finland), head of computational biology and modeling at Beyond Genomics, Inc. (Waltham/MA) and bioinformatician at LION Bioscience Research in Cambridge/MA. As of 2016, Professor Oresic was made a Lifetime Honorary Fellow of the Metabolomics Society. He is co-founder and former chair of the board of the Nordic Metabolomics Society and currently serves in the board of directors of the Metabolomics Society. In 2019, Prof. Oresic co-chaired the 1st Gordon Research Conference on ‘Metabolomics and Human Health’ (Ventura, CA, USA). Previously, he also chaired the Keystone Symposium on Systems Biology of Lipid Metabolism (2015; Breckenridge, CO, USA).
Research projects
Active projects
- Data Infrastructure and Molecular Atlas for Alzheimer's Disease: Connecting Exposome, Gut Microbiome, and Metabolome
- EpiLipidNet - Pan-European Network in Lipidomics and Epilipidomics?
- Human exposure to per- and polyfluoroalkyl substances? Role of the gut microbiome and bile acid metabolism in mediating impact (PFASgut)
- Inflammation in human early life: targeting impacts on life-course health
- LITMUS
- Metabolome in traumatic brain injury - from biomarkers and pathways to clinical translation (pathTBI)
- Novel analytical and computational tools for the assessment of exposure to environmental chemicals
- PAN Protein - plant-based proteins contributing to a healthy and sustainable diet
- Role of environmental exposure in the initiation and progression of non-alcoholic fatty liver disease and insulin resistance
- Late onset of inflammatory bowel disease
- Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease
- Development of toolbox for exposome and metabolomics analyses (MeET)
- X-HiDE
Completed projects
- Blood-based metabolomics to predict severity and patient outcomes in traumatic brain injury (meTBI)
- EPoS - Elucidating Pathways of Steatohepatitis
- Health Consequences of Environmental Exposures in Early Life
- Lipid pathways en route to islet autoimmunity and type 1 diabetes
- Metabolomic and Proteomic markers staging progression to type 1 diabetes in autoantibody positive children
- Mother-infant interactions in relation to potential biomarkers of beta-cell autoimmunity and type 1 diabetes
- Rituximab for schizophrenia spectrum disorder. A pilot study.
- Rituximab - Immunotherapy for Obsessive-Compulsive Disorder. A pilot study.