Madelene Lindkvist

Articles in journals

• Paramel Varghese, G. , Lindkvist, M. , Idosa, B. A. , Sebina, L. S. , Kardeby, C. , Fotopoulou, T. , Pournara, D. , Kritsi, E. & et al. (2022). Novel purine analogues regulate IL-1β release via inhibition of JAK activity in human aortic smooth muscle cells.  European Journal of Pharmacology, 929. [BibTeX]
• Lindkvist, M. , Zegeye, M. M. , Grenegård, M. & Ljungberg, L. (2022). Pleiotropic, Unique and Shared Responses Elicited by IL-6 Family Cytokines in Human Vascular Endothelial Cells.  International Journal of Molecular Sciences, 23 (3). [BibTeX]
• Fälker, K. , Ljungberg, L. , Kardeby, C. , Lindkvist, M. , Sirsjö, A. & Grenegård, M. (2019). Adrenoceptor α_2A signalling countervails the taming effects of synchronous cyclic nucleotide-elevation on thrombin-induced human platelet activation and aggregation.  Cellular Signalling, 59, 96-109. [BibTeX]
• Lindkvist, M. , Fernberg, U. , Ljungberg, L. , Fälker, K. , Fernström, M. , Hurtig-Wennlöf, A. & Grenegård, M. (2019). Individual variations in platelet reactivity towards ADP, epinephrine, collagen and nitric oxide, and the association to arterial function in young, healthy adults.  Thrombosis Research, 174, 5-12. [BibTeX]
• Kardeby, C. , Fälker, K. , Haining, E. J. , Criel, M. , Lindkvist, M. , Barroso, R. , Påhlsson, P. , Ljungberg, L. & et al. (2019). Synthetic glycopolymers and natural fucoidans cause human platelet aggregation via PEAR1 and GPIbα.  Blood Advances, 3 (3), 275-287. [BibTeX]
• Zegeye, M. M. , Lindkvist, M. , Fälker, K. , Kumawat, A. K. , Paramel Varghese, G. , Grenegård, M. , Sirsjö, A. & Ljungberg, L. U. (2018). Activation of the JAK/STAT3 and PI3K/AKT pathways are crucial for IL-6 trans-signaling-mediated pro-inflammatory response in human vascular endothelial cells.  Cell Communication and Signaling, 16 (1). [BibTeX]

Conference papers

• Lindkvist, M. , Paramel Varghese, G. , Rydberg Millrud, C. , Rattik, S. , Grönberg, C. , Liberg, D. & Fransén, K. (2024). Novel antibodies targeting IL1RAP affects markers of vascular inflammation and adhesion in endothelial cells. In:  TOLL 2024 ABSTRACT E-BOOK. Paper presented at TOLL 2024 - Road to translation, Rotterdam, The Netherlands, April 17-20, 2024. (pp. 236-236). [BibTeX]
• Lindkvist, M. , Paramel Varghese, G. , Rydberg Millrud, C. , Rattik, S. , Grönberg, C. , Liberg, D. & Fransén, K. (2023). IL1RAP: a future target to reduce vascular inflammation and adhesion?. Paper presented at Chemical biology workshop - Drug and biomarker discovery Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece, 23-25 November , 2023. [BibTeX]
• Grenegård, M. , Koufaki, M. , Zervou, M. , Fotopoulou, T. , Lindström, E. , Nilsson, K. F. , Lindkvist, M. & Fransén, K. (2023). The cardioprotective, anti-inflammatory and antithrombotic piperazinyl-purine analogue MK177 is a bifunctional drug with promising therapeutic potential. In:  British Journal of Pharmacology. Macmillan Publishers Ltd.. [BibTeX]
• Fotopolou, T. , Ansari, S. , Paramel Varghese, G. , Lindkvist, M. , Ramström, S. , Pournara, D. , Ifanti, E. , Kritsi, E. & et al. (2021). Study of the anti platelet/anti-thromobotic activity of 6-piperazinyl-purien analogues. Paper presented at 18th Hellenic Symposium on Medicinal Chemistry, 25-27 feb. 2021. [BibTeX]

Doctoral theses, comprehensive summaries

• Lindkvist, M. (2020). Impact of Interleukin-6 family cytokine signalling on human endothelial cells and platelets. (Doctoral dissertation). (Comprehensive summary) Örebro: Örebro University. [BibTeX]

Manuscripts

• Lindkvist, M. , Zegeye, M. M. , Sirsjö, A. , Grenegård, M. & Ljungberg, L. U. Comparative evaluation of gp130 signalling cytokines in human endothelial cells : evidence for both specific and overlapping molecular responses. [BibTeX]
• Lindkvist, M. , Paramel Varghese, G. , Göthlin Eremo, A. , Haque, A. , Rydberg Millrud, C. , Rattik, S. , Grönberg, C. , Liberg, D. & et al. IL-1RAP expression in human atherosclerosis : a future target of novel antibodies to reduce vascular adhesion and inflammation?. [BibTeX]
• Lindkvist, M. , Ljungberg, L. U. , Fälker, K. , Ramström, S. , Kardeby, C. , Sirsjö, A. & Grenegård, M. IL-6 trans-signalling inhibits micro- and macro-aggregation induced by epinephrine in human platelets. [BibTeX]